Beyond the Cell Atlas: Theory, Models and Computation


HIC SVNT DRACONES, the story goes, appeared at the margins of ancient maps. Our modern mappings of the cell and its workings should read “Here Be Theory, Models and Computation” because the convergence of diverse approaches is required to probe the mysteries at this frontier. This conference will feature 16 talks from leading researchers from across the globe who are using ideas from mathematics, physics, and computer science to advance our understanding across a range of cellular scales. Let’s explore this new world together on October 28-29 in Berkeley, California.

Program Schedule

Monday, October 28

8:55 a.m. – Welcome to Beyond the Cell Atlas

 


Cells’ Dynamic Architecture

9:00 a.m. – Nanoscale bio-active matter
9:25 a.m. – Phase separation in multicomponent liquid mixtures
9:50 a.m. – Modelling membrane-bound cellular organelles with non-equilibrium dynamics
10:45 a.m. – Navigating an intracellular maze: transport and kinetics in reticulated organelles
11:10 a.m. – Fluid flows shaping morphology
11:35 a.m. – Lightning Talks

 


Cellular Energy, Optimization & Control

1:30 p.m. – Regulatory strategy underlying dimensional reduction in bacterial growth control
  • Terry Hwa, University of California, San Diego

1:55 p.m. – Can we derive the structure of genetic networks from optimization principles?
2:20 p.m. – An optimization-based approach to studying sensory systems
2:45 p.m. – Lightning Talks

 


Cell-Meet-Cell and Cell-Meet-World

3:30 p.m. – Modeling collective cell behavior on curved surfaces
  • Max Bi, Northeastern University

3:55 p.m. – How the immune system keeps up with a changing world
4:20 p.m. – Aging in complex networks and multicellular organisms

Tuesday, October 29

New Tools for Single Cells

9:00 a.m. – Three principles of data science: predictability, computability and stability (PCS)
  • Bin Yu, University of California, Berkeley
9:25 a.m. – Joint analysis of extensive single-cell dataset collections
9:50 a.m. – Modeling perturbations in single-cell genomics
10:40 a.m. – Lightning Talks

 

11:05 a.m. – Enter the matrix: interpreting biological systems through matrix factorization and transfer learning of single-cell data
11:30 a.m. – Modeling coupling between subcellular structures