Frequently Asked Questions

Chan Zuckerberg Biohub Intercampus Research Awards

 

What is the Biohub?

The Chan Zuckerberg Biohub is a non-profit research institute established in 2016 in collaboration with Stanford University, the University of California, San Francisco (UCSF), and the University of California, Berkeley (UCB), to promote fundamental research that elucidates the mechanisms underlying disease and to develop new technologies that will enable fresh avenues of scientific discovery and lead to actionable diagnostics and effective therapies. To achieve these goals, CZ Biohub has established both an in-house research program, focused on infectious disease, cell biology, and technology platform development in areas including Genomics, Genome Engineering, Advanced Optical Microscopy, Data Science, and Bioengineering, and an extramural awards program to support ambitious, otherwise difficult-to-fund research projects led by researchers at Stanford, UCSF, and UCB.

 

Why Intercampus Research Awards? What is the aim?

One of Biohub’s goals is to enhance collaboration between Stanford University, UCSF, and UCB.  These new awards will draw on the strengths of all three institutions to carry out innovative, high-risk research that is likely to have high impact if successful and would not be funded by conventional sources.

 

Is Biohub targeting certain disciplines for applications? What types of proposals is Biohub looking for?

We welcome applications from faculty teams representing diverse disciplines such as engineering, computer science, informatics, the physical sciences, the clinical sciences, and the biomedical sciences. The scope of proposals is open to all areas of biology, biomedical research, and technology development, including areas that are well outside the current Biohub Cell Atlas and Infectious Disease Initiatives.

We want teams to pursue ideas that excite them most and to address the questions or opportunities that team members consider to be fundamentally important based on their shared insights, expertise, and vision.

 


Eligibility

Who is eligible to apply?

Chan Zuckerberg Biohub Intercampus Research Awards are open to teams of faculty members from Stanford University, UCSF, and UCB. Teams can include any number of faculty members but should be led by between three and six faculty members (“project leaders”); this leadership must include faculty from each of the three participating institutions, and each faculty member on a team must be eligible to serve as a principal investigator for federal and other grants.

 

Who is eligible to serve as a principal investigator?

PI-eligibility is determined by each of the participating universities. Stanford University, UCSF, and UC Berkeley have provided the following additional guidelines:

UCSF:

UCSF policy defines Principal Investigator status as academic appointees in the following title groups, provided that their paid appointments are at 50% or more (Emeritus Professors are exempt from the 50% appointment criterion):

  • Professor Series (APM-220)
  • Professor of in Residence Series (APM-270)
  • Professor of Clinical Series (APM-275) (aka Clinical X)
  • Adjunct Professor Series (APM-280)
  • Health Sciences Clinical Professor Series (APM-278)
  • Professional Research Series (APM-310)
  • Librarian Series (APM-360)
  • Emeritus Professors

Assistant- , associate- , and full-rank titles are eligible for PI status.

Stanford University:

The following faculty members are eligible to serve as principal investigators:

  • University Tenure Line (UTL) faculty
  • Non-Tenure Research Line (NTLR) faculty
  • Medical Center Line (MCL) faculty

UC Berkeley:

UCB policy (https://vcresearch.berkeley.edu/research-policies/principal-investigator-status) outlines PI eligible researchers as:

  • Members of the Academic Senate, including Emeriti.
  • Appointees in the Agronomist series, including Emeriti.
  • Appointees in the Adjunct Professor Series
  • Appointees in the Continuing Education series at ranks VII or VIII (for continuing education programs only).
  • Cooperative Extension Specialists
  • Appointees in the Professional Research Series whose salaries are drawn from central campus funds.
  • Clinical professors and other researchers by exceptional approval

 

What if a faculty member will be appointed or become PI-eligible only after the February deadline?

Each team member must be a faculty member at Stanford University, UCSF, or UC Berkeley who is eligible to serve as a principal investigator for federal and other grants effective on the application deadline date, Feb. 15, 2018.

 

Can current Biohub investigators participate?

Current Biohub investigators are eligible to participate but will not receive additional funding.

 


 

Faculty Teams

Why teams?

One of Biohub’s goals is to enhance collaboration between the three Bay Area universities. It is critical that the project leaders and other team members interact and collaborate with each other on an ongoing basis such that they will accomplish much more collaboratively than could be achieved individually with similar funding. Teams should clearly describe in their proposal how the participating team members and their labs will interact to achieve the project goals.

 

Can faculty submit applications as individuals, not part of teams?

No, applications will be accepted only from PI-eligible faculty who submit as teams.

Can faculty outside Stanford University, UCSF, or UC Berkeley be included on teams?

Faculty from other institutions cannot serve as team members and cannot receive direct funding from CZ Biohub under a Chan Zuckerberg Biohub Intercampus Research Award. However, project teams are welcome to enlist other parties as outside collaborators, contractors, or consultants and may use Award funding to pay or provide reimbursement for services related to the proposed research.

 

Could a PI be on more than one team?

We advise against that. We want faculty interested in applying to intensively brainstorm with potential collaborators, and we believe that can only be done well working with a single team.

 

What will be the composition of teams, and will all faculty serve in the same role?

Each team member must be a faculty member at Stanford University, UCSF, or UC Berkeley who is eligible to serve as a principal investigator for federal and other grants. Team members may serve in one of two roles, either as project leader or collaborator. Teams must include a project leader from each of the three participating institutions and may have up to six project leaders total. Teams may include any number of faculty collaborators. Project leaders are expected to fully participate in the Biohub community by attending at least 50% of the biweekly meetings of Biohub Investigators each year. Collaborators may provide expertise, personnel, and other resources to the project, but they do not attend the Biohub Investigator meetings.

 

What happens if one of the team members leaves their institution after the deadline or during the award period? Can that PI still participate if at an institution other than Stanford University, UCSF, or UC Berkeley? Does the team need a replacement?

Participation of each team member is conditioned on their remaining employed by Stanford, UCSF, or UC Berkeley and retaining their academic appointments and labs during the duration of award funding. In addition, each team must include a project leader from each of the three participating institutions throughout the duration of award funding. CZ Biohub retains the discretion to review requests to modify the membership of project teams and to continue or terminate funded awards following the departure of a team member.

 

What else will be expected of selected project teams?

Project leaders of teams funded by Intercampus Research Awards will be expected to participate fully in the Biohub community by attending at least 50% of the biweekly meetings of Biohub investigators each year. With the goal of accelerating the pace of scientific discovery, project teams agree to upload all manuscripts reporting work supported by the award to a preprint server such as bioRxiv.org or arXiv.org upon submission to a peer-reviewed journal.

Intellectual property generated with Chan Zuckerberg Biohub Intercampus Research Award funding or Biohub resources will be jointly owned with the universities; inventor royalty sharing will not be affected and licensing will be led by the Biohub with university approval and in direct consultation with project leaders. The Biohub is committed to facilitating the swift, efficient and strategic development and commercialization of intellectual property in order to make new technologies and treatments available to patients and the research community as expeditiously as possible.

 


Research Awards

How much is the award? How will it be allocated to teams?

Awards will provide $2 million in unrestricted funding over a three year period and give participating research teams access to Biohub’s technology platforms, which include Genomics, Genome Engineering, Advanced Optical Microscopy, Data Science, and Bioengineering. For awarded projects, each team member may receive funds based on budget allocations agreed to by the team as a whole, subject to review and approval of the project budget by CZ Biohub.

 

How can awards be used? Are there use restrictions?

Guidelines on awards will be made available at a later date.

 


 

Applications

Where should applications be sent?

Applications (one per team) should be emailed to CZBIntercampusAwards@czbiohub.org.

What should the team application include?

Each of the following items should be included as separate attachments to the email in PDF file format:

  1. A completed application form (available at https://czbiohub.wpengine.com/competition/) with the title of the proposal, a summary of the proposed research, and the name, affiliation, and contact information of each of the project leaders and faculty collaborators.
  2. A 3-page narrative (including figures and references; 11 point type) describing the proposed research, its significance and potential impact, and how the project leaders, collaborators, and their labs will interact to achieve the project goals.
  3. A concise CV that includes a list of selected publications (no more than 3 pages altogether) for each project leader and collaborator.
  4. Up to 6 selected papers that exemplify key contributions by the project leaders and collaborators relevant to the proposal (to be clear, 6 papers total, regardless of the number of project leaders and collaborators).  Papers may include preprints, publications in press, papers in review, etc.
  5. A separate document that provides concise summaries of the conclusions and significance to the current proposal of each of the attached papers (no more than 200 words per summary).

 

When is the application deadline?

Applications should be submitted by email by 11:59 pm PST on February 15, 2018.

 


Review Process

Who will review the applications?

Applications will be reviewed by an interdisciplinary group of expert reviewers drawn from different institutions.

 

Will teams whose applications are not selected be provided with reviews, scores, or reasons for the decision?

We will inform all applicants of final decisions to award or not award funding, but we will not provide additional information.

 

When will the decisions be made?

Biohub plans to announce recipients of the Intercampus Research Awards by July 15, 2018.

 


 

Inquiries

Where can I get more information and ask additional questions regarding this funding opportunity and the application process?

Inquiries may be sent to the same email address as used to submit applications: CZBIntercampusAwards@czbiohub.org.