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BRIAN KOBILKA, M.D.

Kobilka’s pioneering X-ray crystallographic studies have revealed how the binding of a hormone to the extracellular pocket on a G-protein coupled receptor is transmitted across the cell membrane to trigger a signaling cascade. He is now carrying out structural studies of opioid receptors to identify more effective painkillers with fewer side effects.

Photo of BRIAN KOBILKA, M.D.