Unlocking the inner workings of human biology

July 10, 2025 New CZI AI Model Could Help Scientists Pinpoint Signs of Cancer Cells Read more

July 10, 2025 Teaching AI To Think Like A Cell Read more

May 13, 2025 A gene known for its role in heart disease also drives metastasis in breast cancer Read more

April 8, 2025 Frogs, genes, and cellular antennae: Unlocking the biology of autism Read more

April 3, 2025 Chan Zuckerberg Biohub New York Announces New Investigators for Immune System Research to Improve Human Health Read more

July 10, 2025 New CZI AI Model Could Help Scientists Pinpoint Signs of Cancer Cells Read more

July 10, 2025 Teaching AI To Think Like A Cell Read more

May 13, 2025 A gene known for its role in heart disease also drives metastasis in breast cancer Read more

April 8, 2025 Frogs, genes, and cellular antennae: Unlocking the biology of autism Read more

April 3, 2025 Chan Zuckerberg Biohub New York Announces New Investigators for Immune System Research to Improve Human Health Read more

The CZ Biohub Network pursues grand scientific challenges on a 10- to 15-year time horizon to generate new knowledge and groundbreaking capabilities that significantly decrease the burden of human disease.

San Francisco

Zebrahub: An Atlas of Vertebrate Development

CZ Biohub San Francisco researchers have built a powerful, interactive resource for understanding the developmental biology of the zebrafish, a small, transparent, genetically tractable, and validated model for human disease.

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New York

Unlocking Biological Insights with AI

Learn more about our latest AI model, GREmLN, that could enable faster detection of diseases like cancer.

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Stylized network diagram with interconnected nodes in red, orange, and yellow, representing gene relationships and illustrating CZI’s GREmLN AI model

The inaugural Chan Zuckerberg Biohub in San Francisco is focused on elucidating dynamic cell systems across scales, in health and disease.

TECHNOLOGY PLATFORMS

Bioengineering: A Culture of Hands-On Hacking and Building

Don’t have it? Build it. Our bioengineering team built a UV microscope that could be a faster, cheaper, better way to diagnose malaria.

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INVESTIGATOR PROGRAM

Supporting Early-Stage, Risky Research

We provide unrestricted funding to world-renowned scientists, engineers, and technologists from Stanford University, UC Berkeley, and UCSF, giving these Investigators the freedom to pursue their visionary ideas.

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Chicago

Meet the Chicago Leadership

CZ Biohub Chicago is led by Professor Shana O. Kelley of Northwestern University.

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Chicago

Understanding Inflammation

CZ Biohub Chicago focuses on engineering technologies to make precise, molecular-level measurements of biological processes within human tissues, with the ultimate goal of understanding and treating the inflammatory states that underlie many diseases.

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CZ Biohub Chicago will use embedded sensors and probes to collect biological signals from human tissues with unprecedented resolution. This Biohub will study inflammation, a major driver of disease, and use this new measurement platform to learn how immune cells can malfunction and cause disease.

Chicago

Understanding Inflammation

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CZ Biohub New York will harness and bioengineer immune cells for the early detection, prevention, and ultimately treatment of a wide variety of human diseases.

New York

Harnessing the Immune System

CZ Biohub New York will first harness the natural capabilities of our immune cells to detect and fix abnormalities in our bodies at very early stages. It will then bioengineer immune cells to create new capabilities to detect and potentially treat diseases, including cancers such as ovarian and pancreatic cancer and neurodegenerative diseases like Parkinson's or Alzheimer's, before they become untreatable.

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