Empowering scientists to work on the riskiest, most exciting ideas.
Empowering scientists to work on the riskiest, most exciting ideas.

Empowering scientists to work on the riskiest, most exciting ideas.

The Chan Zuckerberg Biohub is an independent, nonprofit research center that is working to cure, prevent, or manage all disease by the end of the century.

a partnership between

Empowering scientists to work on the riskiest, most exciting ideas. Empowering scientists to work on the riskiest, most exciting ideas.

Many diseases are caused by disorders of the cell. That’s why we support rigorous, quantitative research in
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cell biology.

Quantitative Cell Science
Tabula Sapiens: A First-Draft Single-Cell Transcriptomic Atlas of Two Human Donors, 14 Organs, and 150,000 Cells

This collaborative project provides a molecular characterization of cellular diversity in the human body.

EXPLORE THE DATA
Quantitative Cell Science
OpenCell: A Collection of Localization and Interactome Measurements for Human Proteins

A collaboration between the Leonetti group at CZ Biohub and the Mann Lab at the Max Planck Institute for Biochemistry, along with many other colleagues.

VISIT OPENCELL

Because existing and emerging pathogens continue to threaten human health worldwide, we create and deploy systems to detect and respond to
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infectious disease globally.

INFECTIOUS DISEASE
IDseq: Identifying Pathogens in Metagenomic Sequencing Data

IDseq is a real-time pathogen detection dashboard that helps prevent disease outbreaks around the world. It was created in partnership with scientists and engineers from the Chan Zuckerberg Initiative.

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INFECTIOUS DISEASE
COVID Tracker: The Open-Source Web Platform for COVID-19

CZ Biohub is providing free whole genome sequencing, analysis, and interpretation of SARS-CoV-2 to support the pandemic response. All California Departments of Public Health are invited to participate.

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INVESTIGATOR PROGRAM
Markita Landry: Developing New Nanosensor Technology and Near-Infrared Imaging Platforms

Markita's work includes targeting specific neural circuits in vivo, and supporting closed-loop monitoring and manipulation of neural circuits

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We support high-risk research programs that might otherwise not be funded by conventional sources, and we support the training of the next-generation of scientists and physician-scientists through competitive fellowship programs.

INVESTIGATOR TEAM AWARDS
CZ Biohub Team Award: Defining Host Responses of Virus-Infected and Uninfected Neighbor Cells

The team will focus on how RNA transmission, alterations in viral and cellular RNA stability, and nutritional status can elicit pro- or anti-viral responses in neighbors, drawing on their expertise in culturing 3D human organoids to provide realistic models for the complex interactions that occur between cells in human tissue.

LEARN MORE ABOUT OUR INTERCAMPUS RESEARCH AWARDS

CZ Biohub
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tools and technologies will always be freely available to scientists around the world.

TECHNOLOGY PLATFORMS
Napari: An Interactive, Multidimensional Image Viewer for Python

Created by CZ Biohub's Loïc Royer, Juan Nuñez-Iglesias of Monash University, and Nick Sofroniew of the Chan Zuckerberg Initiative (CZI), Napari is an open-source collaboration involving the Biohub, the CZI Science Technology team, and many other scientists and computational biologists around the world.

SEE IT IN ACTION
IN THE NEWS
Dr. Joe DeRisi in his lab at the CZ Biohub
60 Minutes: Doctors, Scientists Who Warned Officials About Oncoming Pandemic Focus of New Michael Lewis Book

In his new book, Michael Lewis profiles people who tried to sound the alarm about COVID-19 as officials failed to act – including CZ Biohub Co-President Dr. Joe DeRisi.

WATCH
IN THE NEWS
The New York Times Magazine: The Disease Detective

CZ Biohub co-president Joe DeRisi invented a way to find pathogens that scientists didn’t even know to look for. Can it help prevent the next pandemic?

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FEATURED PUBLICATIONS
Fly Cell Atlas: a single-cell transcriptomic atlas of the adult fruit fly Icon

Fly Cell Atlas: a single-cell transcriptomic atlas of the adult fruit fly

READ NOW High-Resolution, Large Imaging Volume, and Multi-View Single Objective Light-Sheet Microscopy Icon

High-Resolution, Large Imaging Volume, and Multi-View Single Objective Light-Sheet Microscopy

READ NOW OpenCell: Proteome-Scale Endogenous Tagging Enables the Cartography of Human Cellular Organization Icon

OpenCell: Proteome-Scale Endogenous Tagging Enables the Cartography of Human Cellular Organization

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http://derisi-zimmer
Infectious Disease
Science and Public Health in the Post-Pandemic Age

Carl Zimmer of the New York Times and CZ Biohub Co-President Joe DeRisi discussed the impact of COVI...

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http://cote
Guest Post
From accelerating particles to advancing public health

An engineering physicist reflects on his role in CZ Biohub’s response to the COVID-19 pandemic...

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Our People
‘Cool’ Collaboration - SARS-CoV-2 Protein Structure

Unique study combines cryoEM, AI to forge atomic-level model of Nsp2...

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Our People
Location, location, location

The organization of cells into discrete compartments such as cilia and endosomes allows for local de...

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