Cell Biology at Scale 2025

The Cell Biology at Scale (CB@S) meeting is co-hosted by the Chan Zuckerberg Biohub New York and Chan Zuckerberg Initiative and aims to bring together a range of stakeholders from diverse disciplines to present recent developments and spark a robust discussion that will articulate key, actionable goals toward true cell biology at scale. Conducting cell biology at scale is not simply an expansion of the number of experiments that can be performed – it represents a fundamental change in the way that such experiments can be conceived and the questions that can be answered. To realize this potential, the field needs to re-evaluate core experimental goals, ask newly accessible biological questions, and adopt scalable technologies for data collection, curation, dissemination, and computational analysis. There is also a need for a collaborative, integrative, and interdisciplinary strategy to combine the capabilities and efforts from diverse laboratories for the robust sharing of techniques or integration of datasets.

Three years ago, we started the CB@S meetings as a first step toward achieving this vision. Every year brings a different geographic location and new scientific topics. This year we hope to touch on a number of themes including:

• Biological dynamics across scales
• In vivo perturbation technologies
• Synthetic biology, organelles and DNA assembly
• Sequence-to-function models
• Multi-modal measurements and modeling

Abstract Submission

Attendees are encouraged to submit an abstract for a short talk which would take place on July 31. Abstracts should be no more than 250 words and must be submitted via the registration form by June 13, 2025 for consideration. Applicants will be notified if their abstract is accepted by July 1, 2025.