Mass Spectrometry Omics

Ryan McClure

Platform Leader

The Mass Spec Omics platform at CZ Biohub Chicago leverages state-of-the-art mass spectrometry to investigate inflammation at both the tissue and cellular levels. Our mission is to deliver deep insights into the roles of proteins, metabolites, and post-translational modifications in chronic inflammatory diseases, with a focus on spatiotemporal resolution. We strive to generate translatable and actionable data that drive research initiatives across the CZ Biohub Network.

We use proteomics to unravel complex protein expression, modifications, and interactions within native and instrumented tissues. High-throughput, data-rich insights reveal the complexities of inflammation, driving innovation and biological discoveries.

Applying metabolomics to map the complex interplay of metabolites and biochemical pathways. Through comprehensive, high-resolution analysis, we uncover the subtle metabolic shifts linked to diseases of inflammation.