Sponsored by the Chan Zuckerberg Biohub with support from the Chan Zuckerberg Science Initiative and celebrating the second anniversary of the founding of the Chan Zuckerberg Biohub.
FRONTIERS IN CELL BIOLOGY DRIVEN BY NEW TECHNOLOGIES
Sept. 24 – 25 | 9 a.m. – 6 p.m.
Session topics:
- Cell Identity and Atlas Efforts
- Cell Architecture – Static and Dynamic
- Model Systems & In Vitro Systems
- Single Cell Genomics & Cellular Flight Recorder
PROGRAM SCHEDULE
MONDAY, SEPTEMBER 24
CELL IDENTITY AND ATLAS EFFORTS
9 a.m. – Welcome to Beyond the Cell Atlas
9:10 a.m. – Single-cell genomics: a stepping stone for future immunology discoveries
- Ido Amit, Weizmann Institute
9:35 a.m. – Tabula Muris, whole-organism single-cell transcriptomics
- Spyros Darmanis, CZ Biohub
10 a.m. – Cellular maps of intact organisms by vDISCO technology
- Ali Ertürk, University of Munich
11 a.m. – From cell atlases to cell and tissue circuits in health and disease
- Aviv Regev, Broad Institute
11:25 a.m. – Reconstructing the maternal-fetal interface one cell at a time
- Sarah Teichmann, Wellcome Sanger Institute
CELL ARCHITECTURE – STATIC AND DYNAMIC
11:50 a.m. – Single particle cryo-EM of membrane proteins
- Yifan Cheng, UCSF/HHMI
1:30 p.m. – Creating a state space of stem cell signatures
- Rick Horwitz, Allen Institute
1:55 p.m. – Dissecting the spatiotemporal subcellular distribution of the human proteome
- Emma Lundberg, KTH Royal Institute of Technology
2:20 p.m. – Opening windows into the cell: bringing structure to cell biology using cryo-electron tomography
- Elizabeth Villa, UC San Diego
3:15 p.m. – GFP-omics, illuminating intracellular architecture
- Manu Leonetti, CZ Biohub
MODEL SYSTEMS AND IN VITRO SYSTEMS
3:40 p.m. – Whole-body single-cell atlases in sponges and annelids reveal repeated parallel evolution of neuronal lineages
- Detlev Arendt, EMBL
TUESDAY, SEPTEMBER 25
CELL IDENTITY AND ATLAS EFFORTS
9 a.m. – Conserved and divergent features of human cortical cell types revealed by single nucleus sequencing
Ed Lein, Allen Institute
9:25 a.m. – Brain architecture and development by single-cell transcriptomics
Sten Linnarsson, Karolinska Institute
9:50 a.m. – Mapping cell type specific genome folding in situ
Alistair Boettiger, Stanford University
10:15 a.m. – CZI’s support of the Human Cell Atlas: next steps
Jonah Cool, Chan Zuckerberg Initiative
MODEL SYSTEMS AND IN VITRO SYSTEMS
11 a.m. – Choanoflagellates as simple models for multicellularity, cell differentiation, and eukaryotic-bacterial interactions
- Nicole King, UC Berkeley/HHMI
11:25 a.m. – Molecular exploration of the brain at single-cell resolution
- Evan Macosko, Broad Institute
11:50 a.m. – Function of RNA by single-cell sequencing in space and time
- Nikolaus Rajewsky, Max Delbrück Center for Molecular Medicine
1:30 p.m. – Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease
- Katalin Susztak, University of Pennsylvania
1:55 p.m. – Reconstructing development and regeneration using single-cell transcriptomics
- Barbara Treutlein, Max Planck Institute
SINGLE CELL GENOMICS AND CELLULAR FLIGHT RECORDERS
2:20 p.m. – Nascent transcriptome profiling by intron seqFISH
- Long Cai, Caltech
2:45 p.m. – Single-cell resolution lineage tracing of cell fate reprogramming
- Samantha Morris, Washington University School of Medicine
3:40 p.m. – Genome architecture mapping in rare cell types
- Ana Pombo, Max Delbrück Center for Molecular Medicine
4:05 p.m. – Imaging whole living organisms with adaptive imaging and deep learning
- Loïc Royer, CZ Biohub
4:30 p.m. – Molecular recording of mammalian embryogenesis
- Michelle Chan, UCSF
4:55 p.m. – Single cell genomics: when stochasticity meets precision
- Sunney Xie, Peking University
5:20 – Closing remarks
