Jacobo Group: Quantitative Tissue Morphogenesis

Our Research

Our group uses a combination of zebrafish transgenesis, cutting-edge imaging tools, and mathematical modeling to understand how tissue architecture emerges from the spatial and temporal dynamics of cell–cell signaling.

We want to understand how organs:

  • create the right number of cells;
  • create the correct cell types;
  • locate cells in their right locations.

This complexity is self-organized through the interactions between cells. To answer these questions we focus on understanding how intercellular signaling dynamics encode the information that drives organ formation.


The 1st Physics of Life Symposium was held at CZ Biohub in San Francisco on January 23, 2023. View videos of the talks here. The 2nd Physics of Life Symposium was held on October 12, 2023.