Chan
Zuckerberg
Biohub
San Francisco
We bring together skilled and creative scientists and engineers to develop new technologies and tackle ambitious research projects, with the aim of understanding dynamic cell systems across scales in both healthy and diseased states.
We also join forces with the Bay Area’s leading academic institutions to support bold, visionary science that can’t be done elsewhere.
CZ Biohub San Francisco is part of the CZ Biohub Network, a group of nonprofit research institutes created and supported by the Chan Zuckerberg Initiative.
Cells & Cell Systems
Cells are the fundamental unit of life. Our goal is to understand dynamic cell systems across scales, in both healthy and diseased states.
Dynamic …
We invent and apply state-of-the-art imaging technologies in living cells and organisms, and develop the computational tools to mechanistically interpret intracellular and intercellular behaviors.
across scales …
Our Research Groups explore cell systems at various scales, from molecules (metabolites, proteins, transcripts), to cells, tissues, organs, and whole organisms, to define cell types, states, and disease phenotypes.
At the grandest scale — in human populations — we enable pathogen surveillance and rapid outbreak response. In collaboration with experts at our partner institutions, both domestically and in low- and middle-income countries, we work to understand infectious disease and advance public health.
in health and disease
We map dynamic changes in cell behavior in response to disease and infection to define underlying mechanisms and to identify potential targets for therapeutic intervention and diagnostic tools.
And our Technology Platforms disseminate the technologies we develop — and the knowledge gained — world-wide through open-access publication and data portals.
INVESTIGATOR PROGRAM
Building community to catalyze innovation
The Investigator Program at CZ Biohub SF is funding research by world-renowned scientists, engineers, and technologists from Stanford University, UC Berkeley, and UCSF.
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Frogs, genes, and cellular antennae: Unlocking the biology of autism
Using frogs as a model organism, CZ Biohub SF Investigator Helen Willsey is revealing surprising connections between autism and hair-like structures on the ...
A vaccine against dementia?
CZ Biohub San Francisco Investigator analyzes health record data to find evidence that a shingles vaccine can lower the chances of developing ...
Arming Burkina Faso scientists with new skills to fight dengue and other infectious diseases
Collaborations between CZ Biohub San Francisco and the Global Fund empower Burkina Faso to develop pathogen genomics testing capacities ...
Location, location: Researchers map proteins across human cells
Organelle Profiling, developed by CZ Biohub San Francisco scientists, is a new tool to understand cells at an unprecedented level of ...
A simple model for an intricate, ever-evolving structure
Scientists use math and physics to address the mystery of just how the endoplasmic reticulum, an organelle essential to life at the cellular level, continually ...
AI powers a better way to diagnose malaria
CZ Biohub San Francisco’s Remoscope shows promise in clinical ...
Family loss spurs quest for knowledge
For CZ Biohub San Francisco research associate Rodrigo Baltazar-Nuñez, science is ...
Our Research
CZ Biohub San Francisco produces scientific research to advance our mission to support the science and technology that will make it possible to cure, prevent or manage all diseases by the end of the century. Explore a selection of publications and preprints from across our institutes and grant partners.
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